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Brian J. Czerniecki, MD, PhD

Degree and Institution

MD, UMDNJ-Robert Wood Johnson Medical School, 1988

Faculty Title

Rhoads-Harrington Professor of Surgery

Administrative Title

Program Director of the PENN Breast Cancer Fellowship

Abramson Cancer Center Title

Surgical Director, Rena Rowan Breast Center
Surgical Director, Immunotherapy



Joint Graduate Program in Immunology

Clinical Expertise

Breast cancer; DCIS; Melanoma; sarcomas.

Research Expertise

Tumor immunology; antigen presentation; dendritic cell-based vaccine and adoptive therapy strategies.

Cancer Programs
Melanoma Program
» Surgical Oncology

Breast Cancer / Rena Rowan Center
» Surgical Oncology

Surgery, Ohio State University Hospital, 1993

Surgical Oncology, National Cancer Institute

Board Certifications

Honors and Award

  • Clinical Oncology Career Development Award, American Cancer Society 1999
  • Komen Foundation Researcher 1998
  • American Cancer Society, Research Scholar 2003
  • Top Doctors in America 2006-2007
  • Americas Top Surgeons 2006-2008
  • Society of University Surgeons 2006


Click here to see my publications

In the News In the News

Contact Information

Brian J Czerniecki

Abramson Cancer Center
Rena Rowan Breast Center
Perelman Center for Advanced Medicine
3rd Floor, West
3400 Civic Center Boulevard
Philadelphia, PA 19104

Office Phone: 215-662-4392
Fax: 215-662-7476

Patricia Rahill
Office Phone: 215-662-4392
Appointment Phone: 215-662-2050
Fax: 215-662-7476

Dr. Czerniecki currently maintains an active clinical practice focusing on the surgical treatment of patients with cancer, he has a major interest in treating patients with breast cancer and is the Co- Director of the Rena Rowan Breast Center. Dr. Czerniecki is a nationally recognized leader in the development of sentinel node mapping for patients with breast cancer with multiple publications on this topic. He also is pioneering studies utilizing breast MRI to better stage and treat patients with newly diagnosed breast cancer, or patients that are at high risk for developing breast cancer. He specializes in breast conservation with oncoplastic techniques for treatment of patients with breast cancer, and has extensive experience performing skin-sparing mastectomies with immediate reconstruction for patients desiring or requiring a mastectomy, even those patients with large breast cancers. Dr. Czerniecki also treats a large number of patients with ductal carcinoma in situ (DCIS) of the breast and has developed clinical trials using vaccines for the treatment and prevention of DCIS and invasive breast cancer. Dr. Czerniecki also is a leading authority on the treatment of melanoma and uses his experience with sentinel nodes. He also has developed and continues to develop vaccines for patients with high risk stage III melanoma. Additional trials are planned for the near future using immune-based therapies for patients with melanoma. Dr. Czerniecki holds several patents on developing dendritic cells for the treatment of patients with cancer.

Dr. Czerniecki also treats patients with soft tissue tumors called sarcomas. There are only about 6,000 of these tumor diagnosed in the US each year. He has extensive experience treating this rare form of cancer using a multidisciplinary approach with radiation therapy. Limb salvage is the main treatment form used for almost all of these patients. Physical therapy and rehabilitation are often part of the treatment for these tumors.